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ICL’s new dissolution kit enables testing of the intrinsic dissolution rate of active pharmaceutical ingredients. The intrinsic dissolution rate of the active pharmaceutical ingredients is measured to depict the dissolution rate of a drug and determine its batch to batch chemical equivalence.
The intrinsic dissolution rate is the rate of dissolution of pure pharmaceutical ingredients when conditions such as surface area, agitation or stirring speed, pH and ionic strength of the dissolution medium are held constant. The determination of this parameter allows labs to screen experimental drug formulations and to understand their behavior under different bio-physical conditions.